AKT3

RAC-gama serin/treonin-protein kinaza jest enzim koji je kod ljudikodirangenomAKT3 sa hromosoma 1.[5][6]

AKT3
Dostupne strukture
PDB Pretraga ortologa: PDBeRCSB
Spisak PDB ID kodova

2X18

Identifikatori
Aliasi AKT3
Vanjski ID-jevi OMIM: 611223MGI: 1345147HomoloGene: 55904GeneCards: AKT3
Lokacija gena (čovjek)
Hrom. Hromosom 1 (čovjek)[1]

Bend 1q43-q44 Početak 243,488,233 bp[1]
Kraj 243,851,079 bp[1]
Lokacija gena (miš)
Hrom. Hromosom 1 (miš)[2]

Bend 1|1 H4 Početak 177,020,073 bp[2]
Kraj 177,258,203 bp[2]
Obrazac RNK ekspresije

Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija transferase activity
protein kinase activity
nucleotide binding
protein serine/threonine kinase activity
GO:0001948 protein binding
ATP binding
kinase activity
Ćelijska komponenta intracellular anatomical structure
membrana
Jedro
citoplazma
Biološki proces protein phosphorylation
GO:0007243 intracellular signal transduction
peptidyl-serine phosphorylation
mitochondrial genome maintenance
signal transduction
Fosforilacija
positive regulation of TOR signaling
positive regulation of cell size
brain morphogenesis
homeostasis of number of cells within a tissue
positive regulation of endothelial cell proliferation
positive regulation of blood vessel endothelial cell migration
positive regulation of angiogenesis
positive regulation of cell migration involved in sprouting angiogenesis
positive regulation of vascular endothelial cell proliferation
positive regulation of artery morphogenesis
negative regulation of cellular senescence
Izvori:Amigo / QuickGO
Ortolozi
Vrste Čovjek Miš
Entrez

10000

23797

Ensembl

ENSG00000117020
ENSG00000275199

ENSMUSG00000019699

UniProt

Q9Y243

Q9WUA6

RefSeq (mRNK)

NM_001206729
NM_005465
NM_181690
NM_001370074

NM_011785

RefSeq (bjelančevina)

NP_001193658
NP_005456
NP_859029
NP_001357003

NP_035915

Lokacija (UCSC) Chr 1: 243.49 – 243.85 Mb Chr 1: 177.02 – 177.26 Mb
PubMed pretraga [3] [4]
Wikipodaci
Pogledaj/uredi – čovjek Pogledaj/uredi – miš

. . . AKT3 . . .

Dužina polipeptidnog lanca je 479 aminokiselina, a molekulska težina 55.775 Da.[7]

10 20 30 40 50
MSDVTIVKEG WVQKRGEYIK NWRPRYFLLK TDGSFIGYKE KPQDVDLPYP
LNNFSVAKCQ LMKTERPKPN TFIIRCLQWT TVIERTFHVD TPEEREEWTE
AIQAVADRLQ RQEEERMNCS PTSQIDNIGE EEMDASTTHH KRKTMNDFDY
LKLLGKGTFG KVILVREKAS GKYYAMKILK KEVIIAKDEV AHTLTESRVL
KNTRHPFLTS LKYSFQTKDR LCFVMEYVNG GELFFHLSRE RVFSEDRTRF
YGAEIVSALD YLHSGKIVYR DLKLENLMLD KDGHIKITDF GLCKEGITDA
ATMKTFCGTP EYLAPEVLED NDYGRAVDWW GLGVVMYEMM CGRLPFYNQD
HEKLFELILM EDIKFPRTLS SDAKSLLSGL LIKDPNKRLG GGPDDAKEIM
RHSFFSGVNW QDVYDKKLVP PFKPQVTSET DTRYFDEEFT AQTITITPPE
KYDEDGMDCM DNERRPHFPQ FSYSASGRE

. . . AKT3 . . .

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. . . AKT3 . . .

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